Searchable abstracts of presentations at key conferences in endocrinology

ea0029p278 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Transient glucocorticoid excess does not cause persisting metabolic changes in mice

Auvinen H. , Romijn J. , Biermasz N. , Boon M. , Havekes L. , Smit J. , Rensen P. , Pereira A.

Introduction: In humans, Cushing’s syndrome (CS) is associated with an increased incidence of the metabolic syndrome, increased cardiovascular morbidity and mortality, even after long-term correction of glucocorticoid (GC) excess.Aim: To evaluate the effects of transient overexposure to GC on the metabolic changes in the long-term in mice.Methods: Single housed male C57Bl/6J mice were given corticosterone (CORT; 50 μg/ml)...