ea0029p278 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012
Auvinen H.
, Romijn J.
, Biermasz N.
, Boon M.
, Havekes L.
, Smit J.
, Rensen P.
, Pereira A.
Introduction: In humans, Cushings syndrome (CS) is associated with an increased incidence of the metabolic syndrome, increased cardiovascular morbidity and mortality, even after long-term correction of glucocorticoid (GC) excess.Aim: To evaluate the effects of transient overexposure to GC on the metabolic changes in the long-term in mice.Methods: Single housed male C57Bl/6J mice were given corticosterone (CORT; 50 μg/ml)...